•  Hypersensitivity to meloxicam or other components of the drug or active substance with a similar effect, such as NSAIDs, aspirin. Meloxicam should not be given to patients who develop symptoms of asthma, nasal polyps, angioneurotic edema or urticaria after taking aspirin or other NSAIDs;
•  Ill trimester of pregnancy (see "Use during pregnancy and lactation.");
•  Children up to 16 years;
•  gastro - intestinal bleeding or perforation, related to previous NSAIDs therapy history;
•  active or recurrent ulcers / bleeding in anamnesis (two or more individual confirmed cases of ulceration or bleeding);
•  severe hepatic impairment;
•  severe renal failure without dialysis;
•  gastro - intestinal bleeding, cerebrovascular bleeding or a history of other bleeding disorders;
•  severe heart failure.

treatment of post-operative pain in coronary artery bypass grafting (CABG).